Table 3. Associations of albumin, LMR and SIS with clinicopathological characteristics.
|
Albumin (g/l) |
LMR |
SIS |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| <40 | ≥40 | P-values | <4.44 | ≥4.44 | P-values | 0 | 1 | 2 | P-values | |
| Characteristics | n=117 | n=324 | n=219 | n=222 | n=185 | n=176 | n=80 | |||
| Age, years | <0.001 | <0.001 | <0.001 | |||||||
| Median | 58 | 55 | 58 | 53 | 52 | 58 | 59 | |||
| IQR | 51–70 | 45–62 | 50–67 | 45–60 | 44–59 | 50–66 | 50–71 | |||
| Sex | 0.742 | 0.032 | 0.071 | |||||||
| Male | 83 | 235 | 168 | 150 | 124 | 137 | 57 | |||
| Female | 34 | 89 | 51 | 72 | 61 | 39 | 23 | |||
| TNM stage | <0.001 | 0.143 | <0.001 | |||||||
| I | 63 | 234 | 141 | 156 | 130 | 130 | 37 | |||
| II | 12 | 18 | 19 | 11 | 10 | 9 | 11 | |||
| III | 37 | 71 | 54 | 54 | 44 | 37 | 27 | |||
| IV | 5 | 1 | 5 | 1 | 1 | 0 | 5 | |||
| Fuhrman grade | 0.049 | 0.009 | 0.001 | |||||||
| 1 | 15 | 57 | 28 | 44 | 36 | 29 | 7 | |||
| 2 | 47 | 155 | 93 | 109 | 94 | 76 | 32 | |||
| 3 | 31 | 75 | 58 | 48 | 36 | 51 | 19 | |||
| 4 | 24 | 37 | 40 | 21 | 19 | 20 | 22 | |||
| Tumour size, cm | 0.017 | 0.002 | 0.001 | |||||||
| <5 | 69 | 230 | 133 | 166 | 139 | 118 | 42 | |||
| ⩾5 | 48 | 94 | 86 | 56 | 46 | 58 | 38 | |||
| Tumour necrosis | <0.001 | 0.001 | <0.001 | |||||||
| Absent | 79 | 269 | 158 | 190 | 160 | 139 | 49 | |||
| Present | 38 | 55 | 61 | 32 | 25 | 37 | 31 | |||
| LVI | 0.034 | 0.025 | 0.005 | |||||||
| Absent | 77 | 246 | 150 | 173 | 143 | 133 | 47 | |||
| Present | 40 | 78 | 69 | 49 | 42 | 43 | 33 | |||
| SSIGN score | <0.001 | <0.001 | <0.001 | |||||||
| 0–3 | 65 | 255 | 143 | 177 | 149 | 134 | 37 | |||
| 4–7 | 40 | 65 | 61 | 44 | 35 | 39 | 31 | |||
| ⩾8 | 12 | 4 | 15 | 1 | 1 | 3 | 12 | |||
Abbreviations: IQR=interquartile range; LMR=lymphocyte to monocyte ratio; LVI=lymphovascular invasion; SIS=systemic inflammation score; SSIGN=the Mayo Clinic stage, size, grade, and necrosis.