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. 2015 Jul 2;113(4):626–633. doi: 10.1038/bjc.2015.241

Table 3. Associations of albumin, LMR and SIS with clinicopathological characteristics.

  Albumin (g/l)
LMR
SIS
  <40 ≥40 P-values <4.44 ≥4.44 P-values 0 1 2 P-values
Characteristics n=117 n=324   n=219 n=222   n=185 n=176 n=80  
Age, years     <0.001     <0.001       <0.001
Median 58 55   58 53   52 58 59  
IQR 51–70 45–62   50–67 45–60   44–59 50–66 50–71  
Sex     0.742     0.032       0.071
Male 83 235   168 150   124 137 57  
Female 34 89   51 72   61 39 23  
TNM stage     <0.001     0.143       <0.001
I 63 234   141 156   130 130 37  
II 12 18   19 11   10 9 11  
III 37 71   54 54   44 37 27  
IV 5 1   5 1   1 0 5  
Fuhrman grade     0.049     0.009       0.001
1 15 57   28 44   36 29 7  
2 47 155   93 109   94 76 32  
3 31 75   58 48   36 51 19  
4 24 37   40 21   19 20 22  
Tumour size, cm     0.017     0.002       0.001
<5 69 230   133 166   139 118 42  
⩾5 48 94   86 56   46 58 38  
Tumour necrosis     <0.001     0.001       <0.001
Absent 79 269   158 190   160 139 49  
Present 38 55   61 32   25 37 31  
LVI     0.034     0.025       0.005
Absent 77 246   150 173   143 133 47  
Present 40 78   69 49   42 43 33  
SSIGN score     <0.001     <0.001       <0.001
0–3 65 255   143 177   149 134 37  
4–7 40 65   61 44   35 39 31  
⩾8 12 4   15 1   1 3 12  

Abbreviations: IQR=interquartile range; LMR=lymphocyte to monocyte ratio; LVI=lymphovascular invasion; SIS=systemic inflammation score; SSIGN=the Mayo Clinic stage, size, grade, and necrosis.