Table 4.

Effects of OLIVE and SOYBEAN on Markers of Inflammation and Infections in Patients Receiving Parenteral Nutrition

Marker		OLIVE		SOYBEAN		OLIVE vs SOYBEAN
	Visit	N	Mean ± SD	N	Mean ± SD	LSGM Ratio (95 % CI)	P-value
Cortisol (nmol/L)	Baseline	214	492.98 ± 284.67	219	499.61 ± 256.24		.
	Day 5	212	371.97 ± 145.68	218	362.98 ± 130.29	1.02 (0.95, 1.1)	0.5677
	EOT/Day 14	82	382.37 ± 193.88	78	395.31 ± 155.08	0.9 (0.77, 1.04)	0.1617
C-Reactive protein (mg/L)	Baseline	214	54.56 ± 54.46	220	56 ± 51.13		.
	Day 5	211	42.33 ± 42.9	216	47.17 ± 42.98	0.95 (0.81, 1.12)	0.5503
	EOT/Day 14	82	20.95 ± 34.44	78	21.92 ± 31.23	0.9 (0.62, 1.31)	0.5785
Procalcitonin (ng/mL)	Baseline	214	0.91 ± 1.84	219	1.19 ± 2.67		.
	Day 5	212	0.36 ± 0.97	218	0.44 ± 1.29	0.98 (0.86, 1.11)	0.717
	EOT/Day 14	82	0.15 ± 0.2	78	0.28 ± 1.1	0.88 (0.71, 1.11)	0.283
sICAM-1 (ug/L)	Baseline	214	264.37 ± 127	220	260.97 ± 128.62		.
	Day 5	209	321.56 ± 158.86	217	304.41 ± 154.53	1.02 (0.94, 1.1)	0.6462
	EOT/Day 14	81	337.84 ± 152.58	78	352.73 ± 197.27	0.96 (0.85, 1.08)	0.4683
Interleukin-6 (ng/L)	Baseline	214	143.03 ± 271.46	220	191.72 ± 705.37		.
	Day 5	211	19.63 ± 57.58	218	20.11 ± 44.19	0.82 (0.69, 0.96)	0.0173
	EOT/Day 14	ND	ND	ND	ND	ND	ND
Malondialdehyde (nmol/L)	Baseline	214	12.46 ± 25.2	219	11.4 ± 21.93		.
	Day 5	211	13.57 ± 27.65	217	12.49 ± 23.13	0.97 (0.87, 1.08)	0.5865
	EOT or Day 14	82	12.65 ± 27.81	78	10.77 ± 21.68	0.86 (0.71, 1.04)	0.115
F2-Isoprostane (ng/mL)	Baseline	214	0.13 ± 0.17	219	0.11 ± 0.14		.
	Day 5	211	0.19 ± 0.33	217	0.14 ± 0.2	1.13 (0.85, 1.5)	0.4006
	EOT/Day 14	82	0.16 ± 0.21	78	0.18 ± 0.29	0.9 (0.58, 1.4)	0.6502

Abbreviations: CI confidence interval, EOT end of therapy, LSGM least square geometric mean, ND not detected, SD standard deviation, sICAM serum intercellular adhesion molecule-1