Table 1. TERT promoter mutations in phyllodes tumors and fibroadenomas of the breast.
Histology | Number of cases | Total mutated | Nucleotide change | Cases mutated |
---|---|---|---|---|
Phyllodes tumor | 46 | 30 (65%) | ||
Benign | 18 | 9 (50%) | c.-146C>T | 3 |
c.-124C>T | 5 | |||
c.-124C>A | 1 | |||
Borderline | 15 | 13 (87%) | c.-124C>T | 13 |
Malignant | 13 | 8 (62%) | c.-146C>T | 1 |
c.-124C>T | 7 | |||
Fibroadenoma | 58 | 4 (7%) | ||
Intracanalicular | 32 | 2 (6%) | c.-124C>T | 2 |
Pericanalicular | 20 | 2 (10%) | c.-124C>T | 2 |
Complex | 6 | 0 |