Table 1. Biochemical and physical parameters in the experimental rats.
Sham | RRM | RRM+vehicle | RRM+PBA | |
---|---|---|---|---|
Body weight (g) | 513±11 | 435±26c | 433±23 | 475±28e |
Renal function | ||||
Plasma creatinine (μmol/L) | 60±3.8 | 133±10.2c | 132±10.3 | 125±10.7 |
BUN (mmol/L) | 6.7±1.0 | 14.2±2.4c | 14.1±2.4 | 12.6±1.1 |
Plasma TG (mmol/L) | 1.05±0.52 | 2.45±0.51c | 2.37±0.51 | 1.54±0.33e |
Plasma glycerol (μmol/L) | 1.95±0.32 | 3.49±0.54c | 3.61±0.54 | 2.62±0.37e |
Plasma FFAs (mmol/L) | 0.52±0.06 | 1.33±0.17c | 1.36±0.19 | 0.95±0.14e |
Data are expressed as mean±SD. n=6.
cP<0.01 vs sham.
eP<0.05 vs RRM+vehicle.
RRM, reduced renal mass; PBA, 4-phenyl butyric acid; BUN, blood urea nitrogen; TG, triglyceride; FFAs, free fatty acids.