Table 1. Summary of methyl eugenol's effects on the recovery from inactivation of the Nav1.7 channel.
Drug (μmol/L) | Methyl eugenol |
Control |
||
---|---|---|---|---|
τ1 (ms) | τ2 (s) | τ1 (ms) | τ2 (s) | |
25 | 20.1 | 3.8 | 16.5 | 3.8 |
(n=4) | (n=4) | |||
125 | 27.4 | 7.1 | 19.8 | 3.3 |
(n=8) | (n=8) | |||
250 | 31.3 | 10.2 | 18.2 | 3.2 |
(n=5) | (n=5) | |||
500 | 40.4 | 23.5 | 20.2 | 4.1 |
(n=5) | (n=5) |
For each concentration of methyl eugenol, the control was perfused with an equivalent concentration of DMSO.