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(A) Cumulative absorption of different concentrations of imperialine in rat intestinal segments (n=5). The concentration of imperialine in the perfusate was (a) 1 μg/mL, (b) 5 μg/mL, and (c) 10 μg/mL. (B) P-gp inhibition study in rat intestinal segments (n=5); (C) NPC1L1 inhibition study in rat intestinal segments (n=5).
