Table 3. Effect of P-gp and NPC1L1 inhibitors on the transport of imperialine across Caco-2 cell monolayers. All results are the mean of measurements from three replicates. ^aMean±SD. ^bP, two-tailed t-test.

C (μg/mL)	AP→BL Paap (×10−6 cm/s)					BL→AP Paap (×10−6 cm/s)
	Nona	Vera	Pb	Ezea	Pb	Nona	Vera	Pb	Ezea	Pb
2	8.81±0.81	8.23±0.48	0.35	8.98±0.45	0.36	7.72±0.45	6.70±0.83	0.18	7.72±0.92	0.80
10	8.40±0.73	8.22±0.10	0.31	8.50±0.91	0.31	7.63±0.22	7.76±0.69	0.50	7.35±0.75	0.90
50	8.19±0.32	8.47±0.42	0.60	8.22±0.11	0.66	7.81±0.26	7.38±0.42	0.20	7.60±0.56	0.58

Abbreviations: Ver, for Verapamil; Eze, for Ezetimibe.