Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 21;18(10):pyv045. doi: 10.1093/ijnp/pyv045

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2015. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 4. — Behavioral effects of antidepressants in mice acutely deprived of brain histamine (HA). (A) Schematic representation of the protocol used to evaluate saline, citalopram, or reboxetine effects on the tail suspension test (TST) in CD-1 mice before and after treatment with alpha-fluoromethylhistidine (α-FMHis). (B) Effects of treatment with citalopram and reboxetine on immobility before and after treatment with a-FMHis. Animals were divided into 7 groups run simultaneously. All data were collated. Saline, citalopram, or reboxetine was given i.p. 30 minutes before testing on day (D)1 and D8. On D7, mice received i.c.v. injections of saline or a-FMHis. Naive mice received no treatment. Represented are means ± SEM of 7 to 11 mice. *P<.05, **P<.01 vs corresponding saline on D1 or D8, ^$$ P<.01 vs same group D7 (ANOVA and Scheffe’s test).