Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The S. aureus SrtA reaction. S. aureus SrtA recognizes protein A by the conserved LPXTG motif. The reaction proceeds through a thioester acyl-enzyme intermediate. This intermediate is resolved by the attack of an amine nucleophile from pentaglycine branched Lipid II, covalently linking Lipid II to a protein substrate (e.g. Protein A) and regenerating SrtA.
