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. Author manuscript; available in PMC: 2015 Nov 17.
Published in final edited form as: Clin Cancer Res. 2012 Jan 6;18(3):654–665. doi: 10.1158/1078-0432.CCR-11-1406

Figure 6.

Figure 6

Combination of MRK003 treatment with γ-radiation. A, Hey1 mRNA levels were significantly increased in OCM1 cells 24 hours after exposure to 4 Gy of γ-radiation as compared with nonirradiated cells (NR) cells (**, P < 0.005). B, Hey1 mRNA levels remained elevated 7 days after radiation, but could be suppressed by MRK003 (*, P = 003; **, P = 0.006; ***, P = 0.0004). C, OCM1 cells were treated with 2 μmol/L MRK003 or DMSO for 5 hours and then exposed to 0 or 4 Gy of γ-radiation in a single dose. Viable cells were counted 7 days after radiation exposure in triplicate experiments (*, P = 0.045; **, P = 0.01).