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. Author manuscript; available in PMC: 2016 Jul 20.
Published in final edited form as: J Genet Genomics. 2015 Jun 24;42(7):355–371. doi: 10.1016/j.jgg.2015.06.003

Fig. 7.

Fig. 7

SPINT2 is a tumor suppressor of GBM.

A: qRT-PCR results demonstrated that SPINT2 was not expressed in U87G cells, but significantly up-regulated in cells transduced with a lentiviral vector expressing SPINT2 B: Forced expression of SPINT2 in U87G cells significantly inhibit cell proliferation as determined by MTT assays. C and D: Soft agar assay results demonstrated that forced expression of SPINT2 inhibited anchorage independent growth of U87G cells. E and F: Force expression of SPINT2 also inhibited formation of primary (E) and secondary tumor spheres (F) from U87G cells.