Table 2.

Geometric mean cytokine concentration (pg/mL) among white controls by cytokine genotype, CLUE II

	Major/major allele		Minor/major allele		Minor/minor allele		P
	N (%)	Mean (95% CI)	N (%)	Mean (95% CI)	N (%)	Mean (95% CI)
TNFα
	GG		AG		AA
rs1800629	335 (66.5%)	8.01 (7.55–8.49)	149 (29.5%)	7.60 (6.96–8.31)	20 (4.0%)	8.40 (6.60–10.69)	0.56
IL10
	GG		AG		AA
rs1800896	141 (27.4%)	2.61 (2.11–2.32)	249 (48.4%)	2.43 (2.07–2.86)	125 (24.3%)	2.76 (2.20–3.47)	0.66
	CC		AC		AA
rs1800872	315 (61.4%)	2.43 (1.36–4.36)	179 (34.9%)	2.82 (2.33–3.41)	19 (3.7%)	2.43 (1.36–4.36)	0.42
IL1β
	TT		CT		CC
rs1143627	236 (48.5%)	0.34 (0.30–0.39)	188 (38.6%)	0.28 (0.24–0.33)	63 (12.9%)	0.28 (0.21–0.36)	0.12
IL8
	TT		AT		AA
rs4073	131 (25.7%)	20.1 (16.7–24.2)	267 (52.5%)	21.6 (19.0–24.5)	111 (21.8%)	19.6 (16.1–24.0)	0.69
IL6
	GG		AG		AA
rs1800797	178 (35.1%)	1.38 (1.25–1.52)	244 (48.1%)	1.36 (1.25–1.48)	85 (16.8%)	1.49 (1.29–1.73)	0.54
	GG		CG		CC
rs1800796	461 (91.1%)	1.37 (1.29–1.46)	44 (8.7%)	1.54 (1.26–1.88)	1 (0.2%)	0.90 (0.24–3.42)	0.47
	GG		CG		CC
rs1800795	175 (34.7%)	1.38 (1.24, 1.53)	247 (48.9%)	1.35 (1.24, 1.47)	83 (16.4%)	1.50 (1.30, 1.74)	0.48