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Pediatric low-grade gliomas (PLGGs) divide into 3 molecular clusters. (A) Self-organizing map (SOM) clustering heat map including the 135 primary PLGGs. (B–D) Distributions among the 3 clusters of histology: (B) supratentorial tumors (ST), (C) infratentorial tumors (IT), and (D) BRAF genomic status (*P < .001, Fisher exact test between members of the starred cluster vs both other clusters). (E) Event-free survival curves for the 3 clusters.
