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. 2015 Jul 21;5:12373. doi: 10.1038/srep12373

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The graph depicts the study design: 322 patients with suspected high grade glioma underwent functional MR imaging and all of them were histologically confirmed as glioma, of which only the 261 patients who succumbed due to glioblastoma progression underwent further analysis. The 30 patients who either died due to other circumstances like accident or surgical complications or were still alive at the end of the data acquisition period were excluded from further analysis. The remaining 31 patients suffering from low grade or anaplastic gliomas were also excluded from further analysis. Depending the 261 patients who succumbed to glioblastoma progression were then distributed according to extent of tumor resection into Friedlein grading (A) and Sawaya grading (B).