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. 2015 Feb 11;5:8374. doi: 10.1038/srep08374

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(A), PPARγ inhibition decreases the expression of PPARγ. ***, P < 0.001. n = 3 per group. Cropped blots were used here and the full-length gels were included in the supplementary information. (B), PPARγ inhibition regulates its downstream target genes. *, P < 0.05; **, P < 0.01; ***, P < 0.001. n = 6 per group. (C), PPARγ inhibitors abolish the beneficial effects of QLQX in improving cardiac function while PPARγ activators failed to provide any additional improvement in cardiac function in the presence of QLQX. ***, P < 0.001. n = 6 per group. (D), QLQX improves the survival rate after AMI and combining PPARγ inhibitors fails to provide additional beneficial effects. **, P < 0.01. n = 6 per group.