Table 3. Hazard ratios for factors that are potentially associated with progression of sarcoidosis.

Characteristics	Per unit for HR	Univariate HR	95% CI	P value	Multivariate HR	95% CI	P value
Age	10 years	1.03	0.81–1.29	0.84	0.92	0.69–1.23	0.58
Sex	Male/female	0.92	0.43–1.97	0.83
BMI	1 kg/m2	1.06	0.96–1.17	0.28
Symptoms	Yes/no	1.71	0.84–3.50	0.14
Histological diagnosis	Yes/no	1.91	0.69–5.33	0.22
Radiographic stage	One stage	1.15	0.72–1.84	0.56	0.92	0.52–1.61	0.76
Number of organs involved	One organ	1.63	1.15–2.29	0.0058	1.71	1.11–2.62	0.015
Serum ACE	≥21.4/<21.4, IU/L	1.35	0.65–2.77	0.42
BAL
Total cells	104/mL	1.00	0.99–1.01	0.87
Lymphocytes	≥17/<17, %	0.99	0.47–2.07	0.98
CD4/CD8 ratio	≥3.5/<3.5	1.42	0.64–3.14	0.38
Pulmonary function tests
FVC % predicted	≥80/<80, %	1.75	0.43–7.09	0.43
FEV1/FVC	≥70/<70, %	1.40	0.36–5.51	0.63

BMI, body mass index; ACE, angiotensin-converting enzyme; FVC, forced vital capacity; FEV₁, forced expiratory volume in 1 second; HR, hazard ratio; CI, confidence interval.