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. 2015 Nov 11;8:3323–3328. doi: 10.2147/OTT.S92443

Table 1.

Characteristics of breast cancer patients with ESR1 mutations (n=28)

Number of patients with ESR1 mutation Total number of patients tested % of patients
ER+ 27 217 12.5
PR+ 24 177 13.6
ER+ or PR+ 27 222 12.1
ER+/HER2 2 30 6.7
Triple negative 1* 119 0.8
Specimen site
 Primary breast tumor 0 0.0
 Local recurrence 3 10.7
 Metastasis 25 89.3

Note:

*

This patient with ER+ primary breast cancer presented with lung metastases and biopsy of one of the lung metastases revealed a triple negative breast cancer.

Abbreviations: ER, estrogen receptor; HER-2, human epidermal growth receptor 2; PR, progesterone receptor.