Table 2.

Decrease in mean paw volume after administration of control, standard, and AgNPs with respect to time

Serial number	Drugs (dose)	Mean paw volume in mL ± SEM, n=6, and percentage edema inhibition
		0 minute	30 minutes	1 hour	2 hours	3 hours
1	Control (1% CMC) (10 mL/kg)	1.88±0.01	2.06±0.04	2.16±0.05	2.31±0.04	2.43±0.06
2	Standard indomethacin (10 mg/kg)	1.6±0.08	1.69±0.03*	1.56±0.04*	1.5±0.02*	1.53±0.06**
3	AgNPs	1.65±0.02	1.9±0.04*	1.75±0.06**	1.8±0.08***	1.84±0.08***

Notes:

^*P<0.001,

^**P<0.01,

^***P<0.05, when control group compared with other treated groups.

Abbreviations: AgNPs, silver nanoparticles; SEM, standard error of the mean; CMC, carboxymethyl cellulose.