Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov 12;10:7031–7044. doi: 10.2147/IJN.S90343

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Mao et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

The inhibition of Dkk1 on the osteogenic and cementogenic differentiation of hPDLSCs cultured on mnHA bioceramics.

Notes: (A) The expression of osteogenic/cementogenic and Wnt signaling-related genes for hPDLSCs cultured on mnHA ceramics or with Wnt signaling pathway inhibitor Dkk1 treatment at day 7. The expression level of mRNA was normalized to GAPDH. *P<0.05. (B, C) ALP staining for hPDLSCs was performed on mnHA bioceramics (B) or with Wnt signaling pathway inhibitor Dkk1 treatment (C) at day 7. The circular insets show ALP staining of the whole disks; and the magnification of B and C is 10.

Abbreviations: Dkk1, dickkopf1; hPDLSC, human periodontal ligament derived stem cell; mnHA, micro-nano-hybrid surface; Runx2, runt-related transcription factor 2; ALP, alkaline phosphatase; OCN, osteocalcin; CAP, cementum attachment protein; CEMP, cementum protein; LRP5, lipoprotein receptor-related protein 5; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.