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Cell apoptosis determined by MTT and flow cytometer analysis.
Notes: (A) Viability of gefitinib-resistant Hela cells after incubation with free gefitinib, gefitinib and shMDR1, gefitinib nanoparticles (NPs), gefitinib NPs combined with shMDR1 NPs, and shMDR1/gefitinib NPs for 48 hours (n=3). (B) Cell apoptosis determined by Annexin V–fluorescein isothiocyanate/propidium iodide staining.
