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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Neurobiol Learn Mem. 2015 Oct 11;125:224–235. doi: 10.1016/j.nlm.2015.10.001

Fig. 5.

Fig. 5

Running during fear extinction increases cfos mRNA induction in direct pathway neurons within the striatum elicited by re-exposure to the extinguished CS during relapse testing (A) depicts a representative photomicrograph showing double cfos+/dynorphin+ FISH in the dorsal striatum, as well as regions chosen for analyses. (B) Within the dorsomedial striatum, the Run/Run group displayed greater cfos+/dynorphin+ expression than Locked/Locked and Run/Context B. (C) No significant group differences were found within the dorsolateral striatum. (D) Within the nucleus accumbens core, the Run/Run displayed greater cfos+/dynorphin+ expression than Locked/Locked and Run/Context B and Locked/Context B. (E) No significant group differences were found within the nucleus accumbens shell. Data are represented as mean ± SEM; +/*p<0.05.