Table 1.

Histotripsy Treatment Results: 58°C Samples.

Heated at 58°C		Histotripsy Lesion (# Samples/Total Samples)
Tissue Type	Heating Duration	No Visible Damage	Surface Damage Only	Partial Damage (No Perforation)	Complete Damage (Perforation)
Tongue
	Control	0/6	0/6	6/6	0/6
	4 Hours	0/6	0/6	0/6	6/6
	8 Hours	0/6	0/6	0/6	6/6
	12 Hours	0/6	0/6	0/6	6/6
Artery
	Control	0/6	3/6	3/6	0/6
	4 Hours	0/6	0/6	0/6	6/6
	8 Hours	0/6	0/6	0/6	6/6
	12 Hours	0/6	0/6	0/6	6/6
Liver
	Control	0/6	0/6	6/6	0/6
	4 Hours	0/6	0/6	0/6	6/6
	8 Hours	0/6	0/6	0/6	6/6
	12 Hours	0/6	0/6	0/6	6/6
Kidney
	Control	4/6	2/6	0/6	0/6
	4 Hours	0/6	1/6	5/6	0/6
	8 Hours	0/6	0/6	0/6	6/6
	12 Hours	0/6	0/6	0/6	6/6
Tendon
	Control	6/6	0/6	0/6	0/6
	4 Hours	5/6	1/6	0/6	0/6
	8 Hours	0/6	6/6	0/6	0/6
	12 Hours	0/6	6/6	0/6	0/6
Urethra
	Control	0/6	5/6	1/6	0/6
	4 Hours	6/6	0/6	0/6	0/6
	8 Hours	3/6	3/6	0/6	0/6
	12 Hours	0/6	6/6	0/6	0/6

Histotripsy treatment results demonstrated that tongue, artery, liver, kidney, and tendon were more susceptible to histotripsy-induced tissue damage after heating at 58°C. Urethra was observed to be less susceptible to histotripsy after heating at 58°C.