Table 1.
Mean ACHS concentrations of three representative PCB congeners and associated sample size required for ACHS-II.
PCB Congener |
Congener characteristics |
Mean ACHS PCB Concentration C(0), in ng/g lipid |
Standard Deviation of ACHS PCB Concentration |
Mean change in PCB Concentration at t=7 years: H0: HL = 14 years |
Mean change in PCB Concentration at t=7 years: HA: HL = 20 years |
Sample Size at 80% Power and α=0.05* |
---|---|---|---|---|---|---|
118 | 5 chlorines Mono-ortho substituted Partially dioxin-like |
70 | 177 | −20.5 | −15.1 | 420 |
153 | 6 chlorines Mono-ortho substituted Non-dioxin-like |
218 | 409 | −63.9 | −47.0 | 232 |
206 | 9 chlorines Tetra-ortho substituted Non-dioxin-like |
40 | 98 | −11.7 | −8.62 | 395 |
HO - null hypothesis, HA - alternative hypothesis, HL – half life.