Table 3. Clinicopathologic Characteristics of High-risk and Low-risk Groups in Validation Set.
| Characteristic | n (%) | High-risk Group (n = 33) n (%) | Low-risk Group (n = 48) n (%) | P |
|---|---|---|---|---|
| Age, yr | 0.061 | |||
| <60 | 24 (29.6) | 6 (18.2) | 18 (37.5) | |
| ≥60 | 57 (70.4) | 27 (81.8) | 30 (62.5) | |
| Sex | 0.502 | |||
| Male | 38 (46.9) | 14 (42.4) | 24 (50.0) | |
| Female | 43 (53.1) | 19 (57.6) | 24 (50.0) | |
| LNs examined | 0.169 | |||
| ≥12 | 57 (70.4) | 26 (78.8) | 31 (64.6) | |
| <12 | 24 (29.6) | 7 (21.2) | 17 (35.4) | |
| pT4 | 1.000* | |||
| No | 75 (92.6) | 31 (93.9) | 44 (91.7) | |
| Yes | 6 (7.4) | 2 (6.1) | 4 (8.3) | |
| Lymphovascular invasion | 0.944 | |||
| No | 69 (85.2) | 28 (84.8) | 41 (85.4) | |
| Yes | 12 (14.8) | 5 (15.2) | 7 (14.6) | |
| Mucin production | 0.048 | |||
| No | 65 (80.2) | 23 (69.7) | 42 (87.5) | |
| Yes | 16 (19.8) | 10 (30.3) | 6 (12.5) | |
| Differentiation | 0.944 | |||
| Well and moderate | 69 (85.2) | 28 (84.8) | 41 (85.4) | |
| Poor | 12 (14.8) | 5 (15.2) | 7 (14.6) | |
| Location | 0.000 | |||
| Right colon | 43 (53.1) | 27 (81.8) | 16 (33.3) | |
| Left colon and rectum | 38 (46.9) | 6 (18.2) | 32 (66.7) | |
| KRAS mutations | 0.562 | |||
| No | 56 (69.1) | 24 (72.7) | 32 (66.7) | |
| Yes | 25 (30.9) | 9 (27.3) | 16 (33.3) | |
| MSI status | 0.893 | |||
| MSS | 40 (49.4) | 16 (48.5) | 24 (50.0) | |
| MSI | 41 (50.6) | 17 (51.5) | 24 (50.0) | |
| Recurrence | 0.029 | |||
| No | 53 (65.4) | 17 (51.5) | 36 (75.0) | |
| Yes | 28 (34.6) | 16 (48.5) | 12 (25.0) |
*
Fisher exact test