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. Author manuscript; available in PMC: 2015 Nov 18.
Published in final edited form as: Cell Rep. 2015 Oct 22;13(5):968–980. doi: 10.1016/j.celrep.2015.09.059

Figure 5. Bactericidal antibiotics induce DNA and RNA oxidation.

Figure 5

(A, B), ELISA-based determination of 8-oxo-dG and 8-oxo-G on total DNA and RNA, respectively. E. coli were treated with 10 mM H2O2, 10 μg/mL Amp, 10 μg/mL Kan, or 250 ng/mL Nor for 60 minutes. Statistical significance is shown (*: p ≤ 0.05) using the untreated control at 60 minutes for determination.