Fig. 6.

Body weight, food consumption, and glucose clearance of SS control and SS-Adora2b mutant rats maintained on a low-salt diet. a Body weight and b food consumption. c, d Glucose clearance determined from fasted rats (6 h) using a standard glucose tolerance test (i.p. administration of 2 g/kg sterile glucose), as described in the “Methods” section. These studies were conducted with rats aged 9–12 (c) or 20–24 (d) weeks. (Insets) Area-under-the-curve calculations. Data are means ± SEM. n = 11–13 male rats/group; *p < 0.05 and **p < 0.01 vs. SS control rats using Student t tests