Table 1.
General and immunological features in patients with and without LGE
| LGE (+) | LGE (−) | p value | |
|---|---|---|---|
| Number | 7 | 33 | |
| Age (y.o.) | 54.0 ± 22.8 | 59.3 ± 11.0 | ns. |
| Female (%) | 6 (86 %) | 29 (88 %) | ns. |
| Disease duration (months) | 49.7 ± 38.2 | 118.3 ± 120.5 | ns. |
| Disease type (limited/diffuse) | 3/4 | 11/22 | ns. |
| Systemic hypertension | 1 (14 %) | 10 (30 %) | ns. |
| Interstitial pneumonia | 3 (43 %) | 15 (45 %) | ns. |
| 30 ≤ eGFR < 60 ml/min/1.73 m2 | 0 (0 %) | 6 (18 %) | ns. |
| Autoimmune antibodies | |||
| Anti-Scl-70 antibody | 1 (14 %) | 4 (12 %) | ns. |
| Anti-centromere antibody | 2 (29 %) | 10 (30 %) | ns. |
| Anti-U1-RNP antibody | 1 (14 %) | 8 (24 %) | ns. |
| Overlaps | |||
| SLE/PM/RA/PN/CT | 0/1/0/0/1 | 3/4/1/1/4 | ns. |
| Medications | ns. | ||
| Corticosteroids | 4 (57 %) | 12 (36 %) | ns. |
| Immunosupressors | 1 (14 %) | 6 (18 %) | ns. |
| Prostanoids | 4 (57 %) | 11 (33 %) | ns. |
| Calcium blockers | 1 (14 %) | 4 (12 %) | ns. |
| ACEI/ARBs | 0 (0 %) | 10 (30 %) | ns. |
The categorical variables were expressed as number and percentage (%) and compared by Chi square test. The continuous variables were expressed as mean ± SD and examined by unpaired t test
ACEI angiotensin converting enzyme inhibitors, ARB angiotensin receptor blockers, CT chronic thyroiditis, eGFR estimated glomerular filtration rate, PM polymyositis, PN polyarteritis nodosa, RA rheumatoid arthritis, SLE systemic lupus erythematosus, ns not significant