Fig. 1.

Comparison of rapamycin-induced size reduction between human hematopoietic stem cells and U937 human monocytic leukemia. a Average hHSC volume 48 h post-rapamycin administration. All hHSCs were ≥8 μm prior to treatment. b Average U937 large and small cell volumes 48 h post-rapamycin administration. Large cells (≥ 13 μm) are denoted with red columns, while small cells (≥ 8 μm) are denoted with blue columns. The effects of 0.48 % EtOH on cell size appear to be minimal. Bars represent the standard error of the mean (SEM) for each individual treatment group.