Table 1.
Effects of rapamycin concentrations ranging from 0.5 to 32 nM on the average cell volume of U937 human monocytic leukemia and human hematopoietic stem cells 48 h post-rapamycin treatment
Rapamycin concentration (nM) | U937 Average volume (μm3) | % Size inhibition U937 | hHSC Average volume (μm3) | % Size inhibition hHSC |
---|---|---|---|---|
0 | 1800 | 0 | 742 | 0 |
0.5 | 1798 | 0.02 | 760 | −0.24 |
1 | 1763 | 2.1 | 723 | 2.6 |
2 | 1752 | 2.7 | 704 | 5.2 |
4 | 1740 | 3.4 | 702 | 5.4 |
8 | 1710 | 5 | 668 | 10 |
16 | 1675 | 7 | 632 | 14.8 |
32 | 1543 | 14.3 | 601 | 19.1 |