Figure 6.

Brain activations and deactivations associated with the main effect of mindfulness meditation and sham mindfulness meditation. Sham mindfulness meditation produced significant activation in the globus pallidus, putamen and right SI of the nose and significant deactivation of the subgenual ACC, PCC, cerebellum and mPFC compared with pre-manipulation. Compared with sham mindfulness meditation, mindfulness meditation produced greater activation in the right putamen/globus pallidus and the PCC. Compared with mindfulness meditation, sham mindfulness meditation was associated with greater activation in the DLPFC, thalamus, PAG, and cerebellum. Conjunction analyses revealed significant overlapping activation in the bilateral putamen and SI corresponding to the nose and deactivation in the mPFC, PCC/precuneous, and cerebellum. Slice locations correspond to standard stereotaxic space.