Table 1.
ChRF expression changes during fear extinction training in different brain areas of extinction-competent S6 and S1 ZnR mice and extinction-deficient S1 mice.
| Region | ChRF | S6 | S1 | S1-ZnR | |||
|---|---|---|---|---|---|---|---|
| Mean difference (%) | P-value | Mean difference (%) | P-value | Mean difference (%) | P-value | ||
| vHC | CHD1 | −32.95 | 0.06 | 54.88 | 0.0003*** | −2.49 | >0.99 |
| CHD5 | −16.51 | 0.24 | −30.06 | 0.035* | −13.47 | 0.6737 | |
| CHD3 | −38.55 | 0.31 | 11.17 | >0.99 | −60.66 | 0.021* | |
| dHC | CHD1 | −27.88 | 0.56 | −40.8 | 0.12 | 9.07 | >0.99 |
| CHD5 | −37.68 | 0.38 | −34.26 | 0.38 | 7.69 | >0.99 | |
| SNF2H | −24.00 | 0.53 | −24.95 | 0.38 | −21.32 | 0.57 | |
| Amy | CHD1 | 9.236 | >0.99 | −20.59 | 0.85 | 39.36 | 0.14 |
| mPFC | CHD1 | 23.06 | 0.51 | −22.01 | 0.82 | 9.81 | >0.99 |
vHC, ventral hippocampus; dHC, dorsal hippocampus; Amy, amygdala; mPFC, medial prefrontal cortex. Negative values indicate a decrease.
*
P < 0.05,
***
P < 0.005.