Table 2.

Burkholderia infection studies performed in lung epithelial cell types.

Biological process	Bacteria	Cell type	References
Adherence	B. pseudomallei	A549	Brown et al., 2002; Kespichayawattana et al., 2004; Essex-Lopresti et al., 2005
		BEAS-2B	Essex-Lopresti et al., 2005
		RPMI-2650
		NCI-H292	Brown et al., 2002
		HEp-2
		KB
Invasion	B. pseudomallei	A549	Jones et al., 1997; Tomich et al., 2002; Kespichayawattana et al., 2004; Chuaygud et al., 2008; Phewkliang et al., 2010
	B. cepacia	A549	Burns et al., 1996; Duff et al., 2006
		16HBE	Duff et al., 2006
		Calu-3
		1y Human	Schwab et al., 2002
	B. cenocepacia	16HBE	Mullen et al., 2007
		CFBE
		1y Human	Taylor et al., 2010
	B. multivorans	16HBE	Mullen et al., 2007
		CFBE
		1y Human	Schwab et al., 2002
Intracellular survival	B. cepacia	A549	Tipper et al., 1998
Intracellular replication	B. pseudomallei	A549	Chuaygud et al., 2008; Phewkliang et al., 2010
	B. cepacia	A549	Duff et al., 2006
		16HBE
		Calu-3
	B. cenocepacia	Immortalized CF epithelium	Sajjan et al., 2006
Bacterial movement	B. cenocepacia	Immortalized CF epithelium	Sajjan et al., 2006
Host response	B. pseudomallei	A549	Utaisincharoen et al., 2005; Wongprompitak et al., 2009
		LA-4	Bast et al., 2014
		1y Murine
	B. mallei	in vivo	Goodyear et al., 2010
	B. thailandensis	A549	Wongprompitak et al., 2009
	B. cepacia	A549	Palfreyman et al., 1997; Fink et al., 2003; Reddi et al., 2003; Mariappan et al., 2013
	B. cenocepacia	A549	Kaza et al., 2011
		16HBE	Kim et al., 2005; Kaza et al., 2011; Wright et al., 2011; Gillette et al., 2013
		Calu-3	Kaza et al., 2011; Gillette et al., 2013
		BEAS-2B	Gillette et al., 2013
		CFBE	Wright et al., 2011
	B. multivorans	A549	Kaza et al., 2011
		16HBE
		Calu-3
		CFBE