Table 3.
Clinical parameters in sulforaphane and placebo group participants before and after trial, Median (interquartile range)
|
SF group (n = 24) |
Placebo group (n = 28) |
|||
| Before | After | Before | After | |
| BMI, kg/m2 | 25.7 (24.2-27.6) | 25.8 (24.2-27.3) | 25.9 (24.6-26.8) | 25.6 (24.5-26.8)a |
| Waist Circumference, cm | 86.5 (81.0-95.0) | 88.8 (82.5-95.0) | 92.3 (88.4-95.3) | 91.4 (88.5-97.1) |
| AST, IU/L | 37.5 (24.8-48.3) | 37.5 (27.0-39.8) | 30.0 (27.5-39.5) | 26.0 (22.5-42.8) |
| ALT, IU/L | 54.0 (34.5-79.0) | 48.5 (33.0-65.3)a | 41.5 (34.0-64.3) | 40.5 (27.0-60.5) |
| γ-GTP, IU/L | 51.5 (40.8-91.3) | 50.0 (37.8-85.3)a | 52.0 (39.5-127.5) | 53.0 (37-99) |
| Alb, g/dL | 4.6 (4.4-4.9) | 4.5 (4.3-4.7)a | 4.6 (4.5-4.7) | 4.6 (4.5-4.8) |
| TB, mg/dL | 0.9 (0.6-1.1) | 0.9 (0.7-1.2) | 0.9 (0.6-1.1) | 0.8 (0.7-1.0) |
| ALP, IU/L | 210 (168-248) | 182 (166-140)a | 230 (206-274) | 231 (214-281) |
| ChE, IU/L | 390 (359-436) | 388 (358-421)a | 398 (369-458) | 406 (370-424) |
| Ferritin, ng/mL | 281 (131-381) | 216 (136-365) | 231 (162-322) | 215 (168-321) |
| UA, mg/dL | 6.1 (5.5-7.0) | 6.0 (5.4-6.8) | 6.4 (5.4-6.8) | 6.1 (5.6-6.7) |
| TG, mg/dL | 146 (118-193) | 135 (95.5-208) | 133 (99.3-166) | 113 (83.0-160) |
| TC, mg/dL | 201 (182-219) | 194 (184-211)a | 196 (183-224) | 207 (184-225) |
| HDL-C, mg/dL | 50.0 (44.0-59.0) | 48.5 (44.8-54.0) | 47.5 (44.8-58.0) | 49.5 (45.0-57.0) |
| LDL-C, mg/dL | 123 (107-138) | 123 (111-141) | 125 (116-142) | 137 (118-146) |
| HbA1c, % | 5.7 (5.4-6.1) | 5.7 (5.5-6.0) | 5.8 (5.5-6.1) | 5.8 (5.5-6.1) |
| FBS, mg/dL | 105 (99.8-113) | 106 (101-115) | 105 (99-115) | 106 (97.5-115) |
| hs-CRP, mg/dL | 0.067 (0.036-0.13) | 0.059 (0.031-0.13) | 0.056 (0.037-0.14) | 0.068 (0.028-0.15) |
| 8-OHdG, ng/mg-CRE | 6.8 (5.5-9.0) | 5.5 (4.9-6.7)a | 6.6 (5.3-8.4) | 6.1 (4.7-7.6) |
| Adiponectin, μg/mL | 6.1 (4.8-7.4) | 4.8 (4.1-7.7)a | 6.3 (4.6-9.5) | 6.1 (4.6-7.9)a |
| Leptin, ng/mL | 5.9 (4.2-7.5) | 5.8 (3.0-8.7) | 7.3 (5.2-11.4) | 6.6 (4.1-10.1) |
a
P < 0.05 vs before. AST: Aspartate-aminotransferase; ALT: Alanine aminotransferase; γ-GTP: γ-glutamyl transpeptidase; Alb: Albumin; TB: Total bilirubin; ALP: Alkali phosphatase; ChE: Choline esterase; UA: Urinary acid; TG: Triglyceride; TC: Total cholesterol; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low density lipoprotein cholesterol; HbA1c: Hemoglobin A1c; FBS: Fasting blood sugar; hs-CRP: High-sensitivity C-reactive protein; 8-OHdG: 8-hydroxydeoxyguanosine; CRE: Creatinine; SF: Sulforaphane.