TABLE 4.

Isolates temporally collected from a single patient

Organism	Isolate	Date collected	Source	Imipenem MICa	blaKPC PCR
E. cloacae	MNCRE41	March 10	Sputum	8, R	+
E. coli	MNCRE46	April 11	Urine	2, I; 4, R (ms)	+
E. coli	MNCRE47	April 11	Sputum	≤1, S	−
E. coli	MNCRE45	April 11	Urine	≥16, R	+
E. coli	MNCRE44	April 13	Sputum	≤1, S (≥16, Rb)	+
E. cloacae	MNCRE51	May 1	Sputum	8, R	+

^aMIC values (in micrograms per milliliter) were reported by the submitting clinical laboratories using Vitek 2 (bioMérieux) automated susceptibility analysis, with the exception of the entry labeled ms, which represents a MicroScan (Siemens Healthcare Diagnostics) automated susceptibility testing result. Letters after numbers indicate resistance status: R, resistant; I, intermediate; S, susceptible.

^bDue to the initial carbapenem-susceptible result in an otherwise highly drug-resistant MIC profile, isolate MNCRE44 was retested using broth microdilution to confirm a carbapenem-resistant phenotype.