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. 2015 Nov 17;59(12):7743–7752. doi: 10.1128/AAC.00831-15

TABLE 7.

Activities of siderophore-free reference compounds against P. aeruginosa in the mouse whole-blood assay

Isolate	MIC (mg/liter) in:
	Aztreonam			Meropenem			Colistin sulfate
	MHB	LB CO₂	Mouse WB CO₂^a	MHB	LB CO₂	Mouse WB CO₂^a	MHB	LB CO₂	Mouse WB CO₂^a
PAO1	4	4	2	0.25	0.12	0.03	0.5	1	2
ARC3502	64	16	8	>64	8	8	0.5	0.5	2
ARC3506	>64	256	128	8	4	4	0.5	0.5	2
ARC4659	16	16	16	0.5	0.03	0.03	0.5	0.5	1
AZ 8-18	8	16	16	8	4	4	0.5	1	1
AZ 32-13	16	64	64	2	0.5	0.06	0.5	0.5	2
JJ 4-36	32	64	32	32	8	4	1	2	2
JJ 5-35	32	64	64	32	8	16	0.5	1	1
JJ 8-16	16	64	64	2	0.5	0.12	0.5	1	2
JJ 11-54	>64	64	64	4	0.5	0.12	1	2	2

^a

Assay results interpreted by the fold increase between the modal MIC in LB CO₂ and the modal MIC in mouse WB CO₂ from three independent tests.