TABLE 1.

Locations of amino acid substitutions in PBP2c in wild-type strains and location of the substitution found in strain 02.5099-D40-A^a

Representative strain	No. of isolates tested	Amino acid substitution at position:
		63	130	145	173	185	269	346	349	466	482	546
LGA251	1	N	V	K	N	R	Y	A	P	R	D	V
0820 A	1							S
52902	2										N
ST20120827	1			I
77964	9				K
Sa13307	4	K
M4A	1								A
71957	14									H
m-40-71	1					L
1198/2006	1		I
51618	1						C
02.5099-D40-A	1											I

^aResidues likely to be in the transpeptidase domain (residues 324 to 665) based on alignment with PBP2a are shown in boldface type.