Quantitative microbiological data plotted as the number of CFU per gram of bone sample. The individual data (empty rhombi), the medians (black bars), the approximate detection limit (2.0 × 103 CFU/g) (dotted line), and the number of rabbits with detectable bacterial load are shown. The TBG and TCS groups had a significantly lower bacterial load at autopsy than that preoperatively (P = 0.001 and P < 0.001, respectively) and than those of the intravenous teicoplanin (P = 0.004 and P = 0.003, respectively) and untreated (P < 0.001) groups. Additionally, the intravenous teicoplanin group showed a significant lower CFU count than that preoperatively (P = 0.045) and than that of the untreated group (P < 0.001).