Skip to main content
. 2015 Nov 17;59(12):7249–7254. doi: 10.1128/AAC.00593-15

TABLE 1.

VT-1161 and fluconazole MICs (μg/ml) against Coccidioides spp. clinical isolates

Parameter Value for the indicated drug (μg/ml)a
C. immitis (n = 23)
C. posadasii (n = 29)
Coccidioides spp. (n = 52)
VT-1161 Fluconazole VT-1161 Fluconazole VT-1161 Fluconazole
MIC range 1–4 4–16 1–4 4–16 1–4 4–16
MIC50 2 8 1 8 1 8
MIC90 2 16 2 16 2 16
GMb MIC 1.48 8.50 1.43 8.19 1.45 8.33
a

C. immitis strains were isolated from patients in central California, while C. posadasii strains were isolated from patients in Arizona (n = 10), California (n = 1), Texas (n = 14), and other miscellaneous locations (n = 4).

b

Geometric mean.