TABLE 2.
Lung fungal burdens at 1 and 14 days posttreatment with VT-1161, fluconazole, or placebo
| Treatment group (dose) | Log10 CFU of lung (mean ± SD)a |
|
|---|---|---|
| Day 1 | Day 14 | |
| VT-1161 (10 mg/kg) | 5.60 ± 0.63 | 5.58 ± 0.82 |
| VT-1161 (50 mg/kg) | 5.24 ± 0.29 | 3.99 ± 0.15 |
| Fluconazole (50 mg/kg) | 5.4 ± 0.21 | 5.32 ± 0.24 |
| Placebo | 7.57 ± 0.18b | 7.57 ± 0.18b |
a
Values are means ± standard deviations at the indicated days posttreatment.
b
Placebo groups from both days of evaluation were combined for purposes of statistical analysis.