Figure 1.

Characterization of Math1-GFP;Dcx-DsRed Mice

Math1-GFP;Dcx-DsRed mice strains were developed by crossing transgenic Math1-GFP and transgenic Dcx-DsRed mice. Cerebellar slices shown in P1 (postnatal day 1) (A), P4 (B), P7 (C), and P11 (D–G) indicate that progenitor cells are present in EGL at P1, increase in numbers at P4 and P7, and reach the number peak at P11, which is consistent with previous reports. MATH1 refers to cerebellar progenitor cells, and DCX is a biomarker of differentiated cells. MATH1 and DCX co-expressing cells represent a cell population at an intermediate stage of differentiation, undergoing a switch from MATH1-expressing cells to DCX-expressing cells, which are termed intermediate cells.

See also Figure S1.

Scale bars, 60 μm for (A–D), (F), and (G) and 200 μm for (E).