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. 2014 Oct 2;5(10):e1436. doi: 10.1038/cddis.2014.414

Figure 1.

Figure 1

The ratio of CD4+Foxp3+ Tregs and TECK concentration in peritoneal fluid is positively correlated with the progression of endometriosis. Number of CD4+Foxp3+ Tregs (a, b) and the concentration of IL-10 (c), TGF-β (d) and TECK (e) in peritoneal fluid from healthy controls (Ctrl) and patients with early stage endometriosis (r-AFS stage I and II) and advanced stage endometriosis (stage III and IV), as determined by flow cytometry and ELISA. (f) The level of TECK secreted by primary ESCs isolated from healthy endometrium, eutopic endometrium and ectopic lesions from patients with endometriosis was analyzed by ELISA. (g) The level of TECK in the supernatant of ESCs from ectopic lesions from patients with endometriosis, from U937 cells and from co-cultured ESCs (from ectopic lesions) and U937 cells. The cells were cultured for 48 h and TECK secretion was assessed by ESLIA. E+U: co-culture d ESCs and U937 cells. Data are expressed as the mean±S.D. P<0.05 was considered to be statistically significant. Values with double asterisks (**P<0.01) are significantly different from those with a signal asterisk (*P<0.05). ns: no statistical difference