Figure 6.

Tumor progression after treatment of animals with different chemotherapy combinations. (a) Time-course body weight progression was measured two times a week for 3 weeks in the eight treatment groups. (b) Time-course of U87-Luc tumor volume progression, as determined by caliper measurements. (c) Normalized tumor volume measured 21 days after the beginning of treatment. (d) Animal survival after treatment with different drug combinations, as indicated in the figure. Each point is the average of the tumor volume of five animals±S.E.M., *P<0.05, **P<0.01 and ***P<0.001. (e) Representative luciferin bioluminescence of U87-Luc tumor growth observed in animals treated with different drug combinations, as indicated, after 21 days