Table 1. Values of heritability, sample size, prevalence, group size, and sampling frequency (when infection time was assumed unknown) considered in the simulated epidemics for validation of the dnIGE model.
| Susceptibility and infectivity h2a,b | Infectivity h2c | Sample sizea | Prevalenced | Group sizeb | Sampling frequency for unknown infection timese |
|---|---|---|---|---|---|
| 0.2 | |||||
| 0.4 | 500 | 0.3 | 2 | ||
| 0.1 | 0.4 | 2 | |||
| 0.33 | 0.5 | 5 | |||
| 0.4 | 0.6 | 10 | 10 | ||
| 0.67 | 0.7 | 30 | |||
| 0.8 | 0.8 | 2000 | 0.8 | 60 | |
| 0.9 | 20 | ||||
| 1 |
The base scenario assumed the values in boldface type and known infection times. Unknown environmental variance was set at 1.
a
To evaluate the effect of heritability and sample size on estimates of heritability and effective contact rates (Figure 2 and Figure S1).
b
To evaluate the effect of heritability and group size on heritability estimates, prediction accuracies, and sire ranking (Figure 4 and Figure S2).
c
To evaluate the effect of genetic variation of infectivity on prediction accuracies (Figure 3).
d
To evaluate the effect of disease prevalence on prediction accuracies (Figure 5).
e
To evaluate the effect of sampling frequency on prediction accuracies (Figure 6).