Fig. 2.

Pathological findings. a Macro photograph of the dissected liver resection demonstrating a lesion in the liver on the left and on the right another lesion in the wall of the gallbladder. b Immunohistological CK 20 stain, demonstrating that the tumor cells of the intrahepatic tumor are CK 20 positive, whereas the liver parenchyma is negative. Magnification ×200. c Immunohistological CK 7 stain demonstrating positive tumor cells in the wall of the gallbladder, supporting the histological outcome that the primary origin of the tumor is the gallbladder. Magnification ×50. d In the sinusoid spaces of the liver, separate strongly enlarged tumor cells are present, corresponding with the morphology of the preexisting myelofibrosis. Magnification ×200.