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. 2015 Nov 18;5:16724. doi: 10.1038/srep16724

Figure 2. Phylogenetic tree of the NBDs.

Figure 2

Green edge, eukaryotes NBDs from half structure transporters; Red edge, N-terminal NBDs from the ABC full or ABC2 structure transporters; Blue edge, C-terminal NBDs from the ABC full or ABC2 structure transporters; Pink edge, NBDs of a specific category of ABCB half structure transporters, may have originated by mitochondrial endosymbiosis; Cyan edge, eukaryotic ABC transporter genes with single NBD structureclustered in the prokaryotic NBD clades; Black edge, prokaryote NBDs. NBDs-half, eukaryote NBDs from half structure transporters; NBDs-N, N-terminal NBDs from the ABC full or ABC2 structure transporters; NBDs-C, C-terminal NBDs from the ABC full or ABC2 structure transporters. Group 1, Group 2 and Group 3 indicate three major clusters for the seven ABC transporter families.