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. 2015 Nov 18;5:16747. doi: 10.1038/srep16747

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(A–F) Original recordings in 20 mM Ca²⁺ Tyrode’s solution at pH_o 5.5, 7.4 and 9.0. Please note that E106D, especially E190Q, conducted very small currents. E106D is insensitive to both pH_o 5.5 and pH_o 9.0, whereas E190Q is insensitive to pH_o 5.5.