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Diagram illustrates the proposed molecular signaling of JWA that reverses cisplatin resistance via the CK2—XRCC1 pathway in human gastric cancer. (a) XRCC1 expression was upregulated by cisplatin. (b) Overexpressed XRCC1 was phosphorylated by CK2. (c) JWA inhibited the expression of CK2. (d) Ubiquitination of XRCC1 was enhanced by the inhibition of CK2
