Table 5.
Site | Tumor | Observed Mutations | |||
---|---|---|---|---|---|
PTEN del. | TP53 R248Q | SPOP F133L | ATRX inversion | ||
Mutation Probabilities → | 0.004 | 0.008 | 0.023 | 0.004 | |
Prostate | P1 | √ | √ | √ | |
P2 | |||||
P3 | |||||
P4 | |||||
P5 | |||||
P6 | √ | ||||
P7 | |||||
P8 | √ | ||||
P9 | |||||
Local Node | L1 | ||||
Lung | B1 | √ | √ | √ | |
Liver | M5 | √ | √ | √ | √ |
Gastric Node | M38 | √ | √ | √ | √ |
Lung | M40 | √ | √ | √ | √ |
Mutations that were not observed in TCGA were assigned a marginal probability of (a+1)−1, where a is the number of cases observed in TCGA.