Fig. 3.

The roles of JNK and NF-κB pathways on expressions of DR4 and DR5 proteins in Huh-7-HBX cells. a The activation of JNK pathways induced by HBX. b The activation of NF-κB pathways induced by HBX. c The role of JNK pathways on expression of DR4 and DR5 proteins induced by HBX. Huh-7-HBX and control cells were cultured in 0.01 % dimethyl sulfoxide (DMSO) in the absence or presence of 20 μM SP600125 for 24 h. Then the expressions of DR4 and DR5 proteins were detected by western blotting analysis. d The role of NF-κB pathways on expressions of DR4 and DR5 proteins induced by HBX. Huh-7-HBX and control cells were cultured in 0.01 % dimethyl sulfoxide (DMSO) in the absence or presence of 10 μM BAY11-7082 for 24 h, and then the expressions of DR4 and DR5 proteins were detected by western blotting analysis