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. 2015 Nov 17;10:148. doi: 10.1186/s13023-015-0364-0

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© Todd et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Evolutionary conservations of substituted residues in three families harbouring novel missense substitutions. Evolutionary conservation of the substituted amino acid in KLHL40 in Family 20 (a), RYR1 in Family 6 (b) and CHRND in Family 10 (c)